Principal Scientist, Target Binding
Generate Biomedicines · Somerville, MA
Bio & Science AIonsiteprincipal$160k–$224k
At a glance
Highlights
- Lead target-binding strategy across multiple biotherapeutic discovery programs.
- Develop novel assays for challenging membrane and multispecific systems.
- Advance target-binding platform by creating novel measurement approaches.
What they offer
- Annual bonus
- Equity compensation
- Competitive benefits package
Ideal candidate
Accomplished biophysics leader passionate about challenging targets and novel methods. Thrives mentoring scientists and guiding cross-functional discovery programs.
Requirements
- Ph.D. in biochemistry, biophysics, analytical chemistry, protein science, chemical biology or related discipline with 8+ years industry experience
- Extensive experience developing and applying quantitative protein-protein interaction and target-binding assays in industry
- Deep expertise with SPR, BLI, KinExA and cell-binding assays including instrumentation and troubleshooting
- Demonstrated success characterizing complex protein interactions and developing novel measurement methods
- Experience leading scientific strategy across multiple cross-functional programs
- Proven experience managing, mentoring and developing scientists and research associates
- Strong quantitative, statistical, communication and problem-solving skills
Lab profile
About Generate Biomedicines
Clinical-stage generative biology company using AI to design novel protein therapeutics.
What they build
- Oncology clinical programs
- Respiratory programs for asthma and COPD
- AI-generated biologic therapeutics
Known for
- Generative AI for protein and drug design
- Protein expression, purification and characterization
- Global Phase 2 and Phase 3 trial execution
- Virtual biologics development and manufacturing model
Key facts
- Founded in 2020
- Headquartered in Somerville, Massachusetts
- Backed by Flagship Pioneering
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