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Scientist I, Synthetic Biology

Generate Biomedicines · Somerville, MA

Bio & Science AIonsiteentry-level$102k–$130k
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At a glance

Highlights

  • Build pooled screens testing hundreds of thousands of protein variants in parallel.
  • Create experimental systems that measure protein function at unprecedented scale.
  • Turn complex biological questions into rich, usable datasets for drug programs.

What they offer

  • Annual bonus
  • Equity compensation
  • Competitive benefits package

Ideal candidate

Experimental synthetic biologist who blends quantitative thinking with benchwork and loves building robust screening platforms. Curious, collaborative and self-driven, you care about data quality and tackling difficult targets like membrane proteins.

Requirements

  • PhD in synthetic/systems biology, bioengineering or related field with 0-1 year experience, or BS/MS with 6+ years relevant experience
  • Hands-on experience designing and running pooled binding screens using purified proteins and cell-based assays
  • Experience designing and building pooled DNA libraries and using NGS to track enrichment
  • Ability to interpret complex screening data and script in Python or similar language
  • Cell-line engineering via CRISPR, lentiviral or transposon methods and membrane protein experience preferred for one role

Lab profile

About Generate Biomedicines

Clinical-stage generative biology company using AI to design novel protein therapeutics.

What they build

  • Oncology clinical programs
  • Respiratory programs for asthma and COPD
  • AI-generated biologic therapeutics

Known for

  • Generative AI for protein and drug design
  • Protein expression, purification and characterization
  • Global Phase 2 and Phase 3 trial execution
  • Virtual biologics development and manufacturing model

Key facts

  • Founded in 2020
  • Headquartered in Somerville, Massachusetts
  • Backed by Flagship Pioneering
More about Generate Biomedicines →
Apply on the lab’s site ↗

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