Director/Senior Director, Molecular Discovery

Highlights

• Own small-molecule programs from hit identification to candidate nomination.
• Ensure autonomous discovery engine delivers validated candidates toward clinic.
• Drive continuous improvement of platform throughput, quality and performance.

What they offer

• Competitive base compensation with bonus potential and early-stage equity
• Medical, dental, and vision coverage
• Employer-paid life and disability insurance
• Flexible time off with company-wide holidays
• Paid parental leave
• Educational assistance program
• Commuter benefits including bike share
• Company-subsidized lunch program

Ideal candidate

Seasoned drug discovery leader with 12+ years driving small-molecule programs to clinic who thrives at the AI-science interface and loves operational rigor, throughput, and turning autonomous platforms into real candidates.

Requirements

• Ph.D. in medicinal chemistry, computational chemistry, chemical biology, or related discipline
• 12+ years in small molecule drug discovery with 5+ years in senior role advancing hit-to-lead to candidate selection
• Demonstrated involvement in programs that delivered clinical candidates
• Deep fluency in medicinal chemistry principles, SAR and lead optimization tradeoffs
• Operational mindset running discovery programs with metrics, milestones and accountability
• Strong working knowledge of ADMET, DMPK and IND-enabling data packages
• Fluency with AI/ML-driven molecular design and judgment on computational output
• Effective communicator translating scientific and operational status for leadership