Principal Machine Learning Engineer, Applied AI
Lila Sciences · Cambridge, MA USA; San Francisco, CA USA · Alewife, Cambridge, MA · San Francisco, CA
CHECKED 15H AGO
Bio & Science AIonsiteprincipal$252k–$336k
At a glance
Highlights
- Shape how Lila's AI models adapt to customer-specific scientific needs.
- Turn frontier model capabilities into reliable, evaluable customer workflows.
- Partner with research and product to deliver end-to-end science workflows.
What they offer
- Competitive base compensation with bonus potential
- Generous early-stage equity
- Medical, dental, and vision coverage
- Employer-paid life and disability insurance
- Flexible time off with company-wide holidays
- Paid parental leave
- Educational assistance program
- Commuter benefits and subsidized lunch program
Ideal candidate
Seasoned ML systems builder who loves closing the last-mile gap to real customer impact in science. You thrive on ambiguous model behavior, customer feedback loops, and mentoring engineers toward reliable products.
Requirements
- Minimum 2-3 years of hands-on post-training experience (SFT, RL methods such as DPO/PPO/GRPO) and evaluation system design
- Strong software engineering skills in Python and modern ML frameworks like PyTorch
- Demonstrated ability to debug ambiguous, high-stakes model behavior using data, traces, logs and feedback
- Experience leading technical work across research and engineering teams
- Deep familiarity with large language models, multi-modal models, or agentic AI systems
- Clear communication skills for translating customer needs and explaining model behavior
Lab profile
About Lila Sciences
Building an autonomous science platform where AI, automation, and biology co-evolve for medicine and materials.
What they build
- Autonomous Science Platform
- AI-designed biologics validated in wet-lab
- Electro-optic materials and photonic devices
Known for
- Large-scale automated data generation
- High-throughput protein purification and analytics
- Protein design and BioML modeling
- Robotic orchestration and lab simulation