Sr Principal/ Principal Software Engineer, Scientific System of Record
Lila Sciences · Cambridge, MA USA; San Francisco, CA USA · Alewife, Cambridge, MA
CHECKED 13H AGO
Bio & Science AIonsiteprincipal$204k–$348k
At a glance
Highlights
- Lead architecture for AI-driven lab execution and scientific memory layer.
- Connect scientific intent to lab reality to close Design-Build-Test-Learn loop.
- Build platform merging AI frameworks with lab workflows and analytics.
What they offer
- Competitive base with bonus potential and early-stage equity
- Medical, dental and vision coverage
- Flexible time off with company holidays and parental leave
- Educational assistance and commuter benefits
Ideal candidate
A technical leader with 8-15 years building large-scale systems who thrives in ambiguity at the intersection of AI, software and science and loves mentoring engineers and turning complex lab processes into elegant platforms.
Requirements
- Bachelor's or Master's in Computer Science, Engineering, or related field
- 8-15 years building and deploying large-scale production systems
- Strong expertise in front-end, backend, or data modeling and system design
- Experience designing scalable architectures, APIs and distributed data systems
- Strong SQL plus NoSQL, vector, graph, search, or lakehouse experience
- Experience in life sciences, ML platforms, lab or automation systems
- Experience with observability, reliability and operational excellence
- Technical leadership mentoring engineers from ambiguity to production
Lab profile
About Lila Sciences
Building an autonomous science platform where AI, automation, and biology co-evolve for medicine and materials.
What they build
- Autonomous Science Platform
- AI-designed biologics validated in wet-lab
- Electro-optic materials and photonic devices
Known for
- Large-scale automated data generation
- High-throughput protein purification and analytics
- Protein design and BioML modeling
- Robotic orchestration and lab simulation