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Associate Scientist, AAV Vector Production

Manifold Bio · Boston Office

Bio & Science AIonsitemid-level$100k–$115k
Apply on the lab’s site ↗

At a glance

Highlights

  • Generate high-quality AAV lots that enable rodent and NHP in vivo studies.
  • Power large-scale in vivo screening of novel proteins using molecular barcoding.
  • Drive datasets that fuel AI-guided protein design for tissue-targeted medicines.

What they offer

  • Annual performance-based target bonus
  • Stock options
  • Comprehensive medical, dental and vision coverage
  • 401(k) plan
  • Flexible paid time off and holidays
  • Perks including on-site gym, onsite lunch and commuter support

Ideal candidate

Meticulous, organized scientist with a few years in biologics who loves hands-on lab work and clear documentation. You thrive juggling projects in fast, collaborative teams bridging experiments and computation to advance breakthrough treatments.

Requirements

  • B.S. or M.S. in biochemistry, molecular biology, chemical engineering, virology or related field with 2-5 years industry experience
  • Hands-on AAV production in HEK293 via triple transfection from ≤1 L to ≥50 L scale
  • Skilled in downstream purification including affinity and ion-exchange chromatography or ultracentrifugation
  • Experienced with qPCR/ddPCR titer assays and capsid quantification via ELISA, western blot and A260/280
  • Familiar with purity assays including SEC-HPLC/UHPLC, CGE, LC-MS and SDS-PAGE with troubleshooting ability

Lab profile

About Manifold Bio

Platform biotech using AI-guided protein design and multiplexed in vivo screening for tissue-targeted medicines.

What they build

  • Tissue-targeted medicines
  • Organism-scale models of living systems
  • AI-guided protein design platform

Known for

  • Massively multiplexed in vivo screening
  • Proprietary molecular barcoding technology
  • In vivo-validated datasets at scale
More about Manifold Bio →
Apply on the lab’s site ↗

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