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Computational Scientist, Assay Development

Manifold Bio · Boston · Boston Office

CHECKED 5H AGO

Bio & Science AIonsite$118k–$138k
Apply on the lab’s site ↗

At a glance

Highlights

  • Design and analyze multiplexed protein library experiments for drug discovery.
  • Invent new quantitative protein engineering assays with experimental scientists.
  • Advance platform for data-driven engineering of tissue-targeted medicines.

What they offer

  • Annual performance-based target bonus
  • Stock options
  • Comprehensive medical, dental, and vision coverage
  • 401(k) plan
  • Flexible paid time off and holidays
  • On-site gym, onsite lunch, and commuter support

Ideal candidate

Collaborative computational biologist passionate about translating complex screening data into therapeutic antibodies. You thrive guiding experiments and building trusted tools at the intersection of computation and wet-lab discovery.

Requirements

  • PhD and/or 4+ years experience in computational biology, bioinformatics, protein engineering or similar
  • Strong understanding of statistics fundamentals and data analysis methodologies
  • Rich experience with Python, agentic coding, data pipeline development
  • Familiarity with version control, test-driven development, and Unix computing
  • Experience with massively parallel reporter assays and high-throughput screening data
  • Experience designing DNA libraries for binders, DMS, phage display or equivalent
  • Experience working with NGS data from library-based experiments
  • Outstanding written and verbal communication skills

Lab profile

About Manifold Bio

Platform biotech using AI-guided protein design and multiplexed in vivo screening for tissue-targeted medicines.

What they build

  • Tissue-targeted medicines
  • Organism-scale models of living systems
  • AI-guided protein design platform

Known for

  • Massively multiplexed in vivo screening
  • Proprietary molecular barcoding technology
  • In vivo-validated datasets at scale
More about Manifold Bio →
Apply on the lab’s site ↗