Scientist II, Delivery for Large Gene Insertion

Highlights

• Lead non-viral DNA donor delivery for recombinase large gene insertion.
• Expand Profluent's gene editing toolbox to unlock new therapeutics.
• Validate delivery approaches in therapeutically relevant cell and in vivo systems.

What they offer

• Equity participation
• 401(k) with employer match
• Health, dental and vision insurance
• Generous PTO and work-life balance commitment
• Professional development in AI-biology intersection

Ideal candidate

Analytical, innovative PhD scientist who thrives leading complex mammalian delivery projects independently and mentoring peers to expand therapeutic gene editing.

Requirements

• PhD in molecular biology, biochemistry, bioengineering or related field with 2-4 years experience
• Proven track record solving problems in gene editing, in vivo delivery or protein engineering
• Ability to develop mechanistic cell-based assays and troubleshoot complex biological systems
• Deep understanding of nucleic acid delivery barriers in mammalian cells
• Hands-on experience in molecular cloning, nucleic acid construct design and mammalian cell engineering
• Extensive experience with NGS-based assays for evaluating genome editing outcomes
• Track record independently leading multifaceted research projects
• Excellent communication skills presenting complex ideas, timelines, risks and results