Scientist II, Molecular Function

Highlights

• Own yeast display platform supplying data for AI protein design models.
• Drive binder campaigns from library design to FACS and NGS readout.
• Shape display direction as binders open new company directions.

What they offer

• Equity participation
• 401(k) with strong employer match
• Comprehensive health, dental and vision insurance
• Generous PTO and commitment to work-life balance
• Professional development opportunities at intersection of AI and biology

Ideal candidate

A yeast display expert with industry experience who loves building platforms hands-on and turning binding data into ML-ready insights. Collaborative, quality-driven, and excited to shape protein engineering in a fast-paced AIxBio startup.

Requirements

• PhD in Molecular Biology, Biochemistry, Protein Engineering, Biophysics, Immunology or related field with 3+ years industry experience
• Deep hands-on experience with yeast surface display including library construction, induction optimization and multi-round selection
• Proven track record generating and screening binder libraries (naive, immune, synthetic or designed)
• Strong flow cytometry and FACS expertise including gating, sort design and interpretation
• Working knowledge of NGS-based screening and deep mutational scanning to produce quantitative binding metrics
• Strong molecular biology skills including cloning, mutagenesis and DNA assembly
• Ability to define assay quality standards for controls, reproducibility and signal-to-noise
• Solid understanding of protein engineering and developability with cross-disciplinary collaboration skills